FROM DISCOVERY TO DEVELOPMENT

Helping Companies Navigate Drug Development Challenges

Management

Michael R. Bleavins, Ph.D., DABT is owner and drug development/biomarker consultant at White Crow Innovation, LLC. He has more than 25 years developing new drugs for common and rare diseases. He joined Parke-Davis/Warner-Lambert in 1987, holding positions of increasing responsibility in laboratory operations and clinical trial support. He retired from Pfizer in 2006 as Executive Director, Safety Translation and Technology. During his tenure at Parke-Davis/Warner-Lambert/Pfizer he supported drug development programs for a broad range of new drug candidates, as well as mechanistic or investigative roles involving the approved products Lyrica®, Neurontin®, Nipent®, Lipitor®, Accupril®, Rezulin®, Omnicef®, Cognex®, Viracept®, Camptosar®, Selzentry®, and Detrol®. For the last six years Mike has consulted for biotechnology companies to advance new molecules, particularly non-traditional compounds, first-in-class drugs, and novel drug platforms where the path is not well trodden.

Michael R. Bleavins

He received a Ph.D. in Environmental Toxicology from Michigan State University, with postdoctoral fellowships at the University of Wisconsin-Madison and the General Motors Biomedical Sciences Research Laboratories. He is a Diplomat of the American Board of Toxicology and a member of several scientific societies. Mike has been responsible for extensive laboratory operations including biomarkers, clinical pathology, cell biology, molecular biology, immunotoxicology, genetic toxicology, investigative pathology, pharmacogenomics, and metabonomics. He has 60+ publications in these areas and multi-species effects of toxic agents. Mike also was the lead editor and a contributor to the book "Biomarkers in Drug Development: A Handbook of Practice, Application, and Strategy". He has extensive expertise in pre-clinical toxicology, biomarker development, validation, and translation, as well as drug development.

Mike also has a full clay studio where he produces hand-made art tiles. The "Face Tectonics" series is based on facial impressions and computer-assisted manipulation of the resulting images. These tiles have been popular with several of clay-tile collectors, as well as the individuals whose faces made the original prints. Other tile designs featuring horseshoe crabs, toads, trilobites, and fossil fish have been used in custom installations in private homes.